A:Answer I had to search ASUS website as I was asking the same thing myself. Look here....
https://www.asus.com/supportonly/FX506LI/HelpDesk_Manual/
According to the "Upgrade Guide" both SODIMM slots are removable, the NVME is removable, and there's space for a 2.5" ssd/hdd as well. I ordered one to replace my 9yo HP DV6 core i7 with discrete 7660xt. I hate HP whitelisting for upgrades.
I can't find anything close in price for a 1650ti, and I'm not willing to pay $100-200 more just to get a Ryzen with a regular 1650. This core i5 is benching faster 1-core and 2-core speeds than 4000series Ryzen, so I'm not upset. I'm just glad the strong AMD showing is already driving 10th gen Intel prices down so low! We'll see how hot thermals get on this 10th gen ASUS setup...