A:Answer An average Lithium-ion battery would survive around 500~1,500 charging cycles. Now, according to techs out there who've tested it, it is not ideal to use it from 100-0 in one go, this would degrade the battery's life span badly.
There is no harm in keeping the speaker plugged in, what is harmful, is heat. Keeping it plugged in while using it might cause the battery to heat up to such degree that it would also degrade your battery.
With these things in mind, what we can advise is - it is okay to leave it plugged in, the charger and the batteries right now are smarter than we think, there is no such thing now as "overcharging". But since heat is something we would like to avoid, unplug it when you use it and charge the speaker a little every time you have a chance to. Lithium-ions takes charge better when done on small frequent charges than going from 0-100. And last note, NEVER flat your battery out.