A:Answeryes it can be programmed to open applications. it can be programmed for macros, button clicks, app shortcuts, media controls. the list of things it can be told to do is actually rather impressive for a mouse.
A:AnswerNo, it fits in my hand surprisingly well (because it doesn't really look like it would) and I have fairly big hands. The buttons on the side are in just the right spot for your thumb so you don't have to move it too far out of position to reach them.
I have gamed for longer than a few hours and usually my wasd keyboard (left) hand will get tired before my mouse hand.
A:AnswerIt does not have a unifying adapter. It uses it's own adapter in order to have full bandwidth when the mouse is in performance mode to not experience virtually any lag
A:AnswerJust wireless USB. The other downside it does not play well with other Logitech keyboards or mice (the ones that allow you to share the USB dongle with keyboard and mouse).
