A:Answer Go to https://www.myharmony.com/en-us/ and select "Compatibility" then put in the manufacturers name and model number in the appropriate fields. Sony 65 4k tv Model XBR-65X850D is compatible. So is Amazon Alexa (Echo, Echo Dot) so you can use your voice to turn on the TV and many other functions that are normally available through the remote (with Harmony Remote + Hub). Just having 1 remote for the TV, the Sound bar, the stereo, and the Blue-Ray player has made my coffee table available for other things. That alone is worth it to me.