A:Answer Either enter BIOS SETUP to select the Windows 10 USB or similar as your first boot drive and save the setting changes on exit and restart with the drive plugged in to the USB port
(Entering BIOS Setup is usually accomplished by hitting F1, F2, or Delete Key at splash screen on boot up. Depends on manufacturer which key.)
OR
Hit the F12 Key at your boot up and choose your device from the list given.
Windows 10 installation is pretty clear after that.
Along with the USB Drive in the box, there's a Key Card in a sleeve too. You need this to enter when asked during Windows 10 setup.
You should have an internet connection ready (and info ready) and also have an email and password ready to sign up for a Microsoft account, if you don't have one already. You can skip this until later.
After Win10 is installed and you have an internet connection Activate windows 10, go to settings, and find "windows update", look for Activation on the left side. Then go to Windows Update on the right and start downloading your updates till you have version 1909 installed. If you have a driver disc for your system install the drivers. Windows update may find them for you.
Win10 has some protection with it, but if you have it, install a security suite. Virus protection and Firewall, etc..
Hope this helps you....