A:Answer Yes it would work with a system with the ryzen 3 2300x. It should work with just about any CPU. As long as you have a motherboard with an open PCI-e x16 slot, a spare 6-pin power connector, and a power supply that can supply enough watts(which is really easy to do my build has a 450-watt power supply which should be fine for most builds using this GPU, but depending on your other components you may need more watts to be safe and stable).