A:Answer Yes you can off either an SD card or a usb flash drive but you need to make a folder named (retrobit games) and all games must be placed in that single folder for them to work. This Super Retro-cade will work with NES, SNES, Gameboy, Gameboy color, Gameboy advance, Genesis, Game gear, Genesis CD (requires bios files to work), Mame arcade, and Only v1.1 units support PCE (TurboGrafx 16) ROMs. Hope this helps! for more assistance there's plenty of information and videos online to show how this works!