A:Answer Yes, This model has 2 total inputs, 1 HDMI and 1 DisplayPort so any NVIDIA card from the GTX 900, GTX 10, GTX 16, RTX 20, RTX 30, RTX 40 and upcoming RTX 50 series will work just fine and should be capable of 4k on at least 1 display but this model does not have NVIDIA G - SYNC feature built in which mostly syncs the refresh rate and prevents screen tearing, studdering and lag for a smoother gmaing experience but is not necessary and most people cant tell any difference and the few who do can only do so when shown side by side. If any of those issues of concern you're better off with a monitor that has a higher refresh rate than 60Hz