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Yes, as long as you can find a way to mount this 2.5" drive properly in your Lenovo B50-30 AIO Desktop.
Sorry, there was a problem. Please try again later.I would think so. Never worked on an All-in-one before So never had the chance to examine one but I believe there is an internal bay for an ssd or hdd. The connectors should be the same. In either case with an adapter or dock one could conceivably connect the drive via usb (I'm currently doing this with the ssd from my other computer which was smote by lightning recently on my wife's computer). Hope this helps. -Kevin-
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