A:Answer Do not clone your system disk to a USB-drive, Windows cannot boot from a USB-drive.
The cloning should be done from Acronis Bootable Media (created on CD/DVD or Flash). When cloning from Acronis Bootable Media, you do not need to have an operating system or an Acronis product installed on the new drive. You do not even need to have the new drive formatted to do the cloning. For information on Acronis Bootable Media see Acronis bootable media: https://kb.acronis.com/content/1537
Even when you start cloning in Windows, the computer will reboot into the Linux environment the same as when booting from the rescue media. Because of this, it is better to clone under rescue media. For example, there may be a case when your hard disk drives are detected in Windows and not detected in Linux. If this is the case, the cloning operation will fail after reboot. When booting from the rescue media, you can make sure that Acronis True Image detects both the source and target disks before starting the cloning operation. Cloning of both desktop and laptop hard disks is supported.