A:Answer Do you mean Apple or PC? If so, then yes however you will have to format it for the MacOS filesystem as it comes out of the box as NTFS(windows filesystem).
Something to consider is the exFAT file system which is supported by windows,Mac, AND even linux directly can all share files. If you need to have files shared across windows and mac exfat would work best most likely. Or, you can partition the drive to have different sections for each but the Macs HFS+ filesystem CANNOT be read by windows and Mac can only read(not write to NTFS) so exfat allows both to play nicely.