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Best Buy customers often prefer the following products when searching for ergonomic computer mouse.

If you spend a lot of time on the computer, you may want to consider an ergonomic mouse. Ergonomic mice are designed to reduce the stress on your hand and wrist by providing a more natural design. This can help prevent or reduce future injury and improve your comfort and productivity. Browse the top-ranked list of ergonomic computer mice below along with associated reviews and opinions.

Main Results
  1. Logitech - M310 Wireless Optical Ambidextrous Mouse - Wireless - Black - Front_Zoom
    Top comment

    "I can navigate really well on computer with this mouse. I purchased a second one for my household....Very comfortable/ergonomic, good value. Like this mouse a lot!...Very comfortable/ergonomic, good value...Great mouse for computers"

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    Product Description

    Logitech M310 Wireless Mouse is an easy-to-use, full-size mouse that feels just right. Feel comfortable for hours on end - in your right or left hand - thanks to its contoured, ambidextrous design with soft rubber side grips. M310 comes with a plug-and-forget nano USB receiver that is small enough to stay in your USB port so you won't lose it no matter where you take your laptop. Navigating on your PC or Macbook is simple, with smooth, responsive tracking and Logitech Advanced 2.4 GHz wireless connectivity. For hassle-free use and extreme reliability and durability, choose M310 wireless mouse.
    See all Wireless & Bluetooth Mice
    Top comment

    "I can navigate really well on computer with this mouse. I purchased a second one for my household....Very comfortable/ergonomic, good value. Like this mouse a lot!...Very comfortable/ergonomic, good value...Great mouse for computers"

    See all customer reviews

    Product Description

    Logitech M310 Wireless Mouse is an easy-to-use, full-size mouse that feels just right. Feel comfortable for hours on end - in your right or left hand - thanks to its contoured, ambidextrous design with soft rubber side grips. M310 comes with a plug-and-forget nano USB receiver that is small enough to stay in your USB port so you won't lose it no matter where you take your laptop. Navigating on your PC or Macbook is simple, with smooth, responsive tracking and Logitech Advanced 2.4 GHz wireless connectivity. For hassle-free use and extreme reliability and durability, choose M310 wireless mouse.
    See all Wireless & Bluetooth Mice
    Your price for this item is $22.99
    See all Wireless & Bluetooth Mice
  2. Logitech - M170 Wireless Compact Optical Ambidextrous Mouse - Wireless - Black - Front_Zoom
    Top comment

    "This mouse is really ergonomic! Light weight and easy to handle!...Very good mouse...Nice hand feel, ergonomic mouse, easy to use, logitech user since 90's"

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    Product Description

    NOW IS WIRELESS. With Logitech M170 Wireless Mouse, choose the reliability of a cord with the convenience of wireless – and a 33-foot range – thanks to Logitech Advanced 2.4 GHz wireless technology. This affordable mouse works for up to 12 months on a single AA battery. Set up is simple – just plug the tiny wireless receiver into a USB slot. There's no hassle with pairing or software installation, and M170 is compatible with Windows, Mac and Chrome.
    See all Wireless & Bluetooth Mice
    Top comment

    "This mouse is really ergonomic! Light weight and easy to handle!...Very good mouse...Nice hand feel, ergonomic mouse, easy to use, logitech user since 90's"

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    Product Description

    NOW IS WIRELESS. With Logitech M170 Wireless Mouse, choose the reliability of a cord with the convenience of wireless – and a 33-foot range – thanks to Logitech Advanced 2.4 GHz wireless technology. This affordable mouse works for up to 12 months on a single AA battery. Set up is simple – just plug the tiny wireless receiver into a USB slot. There's no hassle with pairing or software installation, and M170 is compatible with Windows, Mac and Chrome.
    See all Wireless & Bluetooth Mice
    Your price for this item is $12.99
    Save $2
    The comparable value price is $14.99
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  3. Insignia™ - Bluetooth 6-Button Ergonomic Mouse - Wireless - Black - Front_Zoom
    Top comment

    "Insignia mouse......Good ergonomic feel. Was on sale which inspired purchase....works very also great ergonomics for the everyday computer user."

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    Product Description

    Whether you just got a new computer or are simply upgrading your current setup, you can’t go wrong with this Insignia Bluetooth 6-Button Ergonomic Mouse. It uses reliable Bluetooth technology to easily connect to your Windows, macOS, ChromeOS, iPadOS and Android systems. A sleek, ergonomic build is comfortable enough for everyday use, and 6 buttons provide plenty of simple, intuitive control options. Optical technology makes this mouse more than suitable for a variety of daily uses. Finally, a power switch and LED indicators help to preserve the battery life of your mouse. Upgrade your setup with this easy-to-use Insignia mouse.
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    Top comment

    "Insignia mouse......Good ergonomic feel. Was on sale which inspired purchase....works very also great ergonomics for the everyday computer user."

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    Product Description

    Whether you just got a new computer or are simply upgrading your current setup, you can’t go wrong with this Insignia Bluetooth 6-Button Ergonomic Mouse. It uses reliable Bluetooth technology to easily connect to your Windows, macOS, ChromeOS, iPadOS and Android systems. A sleek, ergonomic build is comfortable enough for everyday use, and 6 buttons provide plenty of simple, intuitive control options. Optical technology makes this mouse more than suitable for a variety of daily uses. Finally, a power switch and LED indicators help to preserve the battery life of your mouse. Upgrade your setup with this easy-to-use Insignia mouse.
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    Your price for this item is $29.99
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  4. Contour - Unimouse Wired Ergonomic Mouse - Wired - Black - Front_Zoom

    Product Description

    We’re impressed with Contour Design’s Unimouse, a true innovation in the world of ergonomic computer accessories–not only does it allow the user to rotate his wrist to its most neutral position, it also features graduated adjustment angles for the mouse body, from 35 to 70 degrees, so the user can choose the most comfortable wrist pronation angle and make adjustments to it as they adapt to more ergonomic mousing.
    See all Ergonomic Mice

    Product Description

    We’re impressed with Contour Design’s Unimouse, a true innovation in the world of ergonomic computer accessories–not only does it allow the user to rotate his wrist to its most neutral position, it also features graduated adjustment angles for the mouse body, from 35 to 70 degrees, so the user can choose the most comfortable wrist pronation angle and make adjustments to it as they adapt to more ergonomic mousing.
    See all Ergonomic Mice
    Your price for this item is $79.99
    See all Ergonomic Mice
  5. Insignia™ - Wireless Optical 3-Button Mouse - Wireless - Black - Front_Zoom
    Top comment

    "I bought this looking for a more ergonomic mouse. I got a cramp & a weird thing happened to my hand from using the regular mouse. ...Compact, Smooth, and Responsive Mouse...Insignia Slim Wireless Mouse I picked this mouse because it’s small, wireless, and will work on any computer. "

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    Product Description

    Whether you just got a new computer or are simply upgrading your current setup, you can’t go wrong with this Insignia Wireless Optical 3-Button Mouse. Its plug-and-play technology easily connects to your Windows, macOS or ChromeOS system with a simple USB dongle. A simple design works for both right and left-handed users, and a timeless layout consists of 3 programmable buttons. Finally, optical technology makes this mouse more than suitable for a variety of daily uses. Upgrade your setup with this easy-to-use Insignia mouse.
    See all Wireless & Bluetooth Mice
    Top comment

    "I bought this looking for a more ergonomic mouse. I got a cramp & a weird thing happened to my hand from using the regular mouse. ...Compact, Smooth, and Responsive Mouse...Insignia Slim Wireless Mouse I picked this mouse because it’s small, wireless, and will work on any computer. "

    See all customer reviews

    Product Description

    Whether you just got a new computer or are simply upgrading your current setup, you can’t go wrong with this Insignia Wireless Optical 3-Button Mouse. Its plug-and-play technology easily connects to your Windows, macOS or ChromeOS system with a simple USB dongle. A simple design works for both right and left-handed users, and a timeless layout consists of 3 programmable buttons. Finally, optical technology makes this mouse more than suitable for a variety of daily uses. Upgrade your setup with this easy-to-use Insignia mouse.
    See all Wireless & Bluetooth Mice
    Your price for this item is $19.99
    See all Wireless & Bluetooth Mice
  6. Insignia™ - Bluetooth 3-Button Mouse - Wireless - Black - Front_Zoom
    Top comment

    "Good Mouse...Compatible with all computers in the house. Easy to use...Great mouse purchase...This mouse works great with my new apple computer."

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    Product Description

    Whether you just got a new computer or simply upgrading your current setup, you can’t go wrong with this Insignia Bluetooth 3-Button Mouse. It uses reliable Bluetooth technology to easily connect to your Windows, macOS, ChromeOS, iPadOS and Android systems. A slim, ambidextrous design works for both right and left-handed users, and a timeless layout consists of 3 buttons. Finally, optical technology makes this mouse more than suitable for a variety of daily uses. Upgrade your setup with this easy-to-use Insignia mouse.
    See all Wireless & Bluetooth Mice
    Top comment

    "Good Mouse...Compatible with all computers in the house. Easy to use...Great mouse purchase...This mouse works great with my new apple computer."

    See all customer reviews

    Product Description

    Whether you just got a new computer or simply upgrading your current setup, you can’t go wrong with this Insignia Bluetooth 3-Button Mouse. It uses reliable Bluetooth technology to easily connect to your Windows, macOS, ChromeOS, iPadOS and Android systems. A slim, ambidextrous design works for both right and left-handed users, and a timeless layout consists of 3 buttons. Finally, optical technology makes this mouse more than suitable for a variety of daily uses. Upgrade your setup with this easy-to-use Insignia mouse.
    See all Wireless & Bluetooth Mice
    Your price for this item is $17.99
    See all Wireless & Bluetooth Mice
  7. Best Buy essentials™ - Wireless Optical Standard Ambidextrous Mouse with USB Receiver - Wireless - Black - Front_Zoom
    Top comment

    "bluetooth mouse...the mouse works well. it feels ergonomic as well. I would recommend this product...It takes up to 10 mins to pair or for tge computer to sense that there’s a mouse. And that’s with all the computers I’ve tested"

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    Product Description

    Eliminate the most common computer mouse issue—the cord. With the Best Buy Essentials Wireless Mouse with USB Receiver, you can navigate the web with speed and accuracy. Compatible with both Windows and Mac computers, simply insert the included nano receiver into one of your computer’s USB ports to wirelessly connect the mouse. It has just 3 buttons and an ambidextrous design for simple control. Optical technology detects when the mouse moves to deliver an accurate 1600 DPI response. We also included a AA battery, so you won’t have to worry about keeping the mouse powered until the LED indicator starts to blink. Let us improve your computer navigation by going wireless with this Best Buy-backed mouse.
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    Top comment

    "bluetooth mouse...the mouse works well. it feels ergonomic as well. I would recommend this product...It takes up to 10 mins to pair or for tge computer to sense that there’s a mouse. And that’s with all the computers I’ve tested"

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    Product Description

    Eliminate the most common computer mouse issue—the cord. With the Best Buy Essentials Wireless Mouse with USB Receiver, you can navigate the web with speed and accuracy. Compatible with both Windows and Mac computers, simply insert the included nano receiver into one of your computer’s USB ports to wirelessly connect the mouse. It has just 3 buttons and an ambidextrous design for simple control. Optical technology detects when the mouse moves to deliver an accurate 1600 DPI response. We also included a AA battery, so you won’t have to worry about keeping the mouse powered until the LED indicator starts to blink. Let us improve your computer navigation by going wireless with this Best Buy-backed mouse.
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    Your price for this item is $9.99
    See all Wireless & Bluetooth Mice
  8. Best Buy essentials™ - Lightweight Bluetooth Optical Standard Ambidextrous Mouse with 6-Button - Wireless - Black - Front_Zoom
    Top comment

    "Nice Mouse...This device is very reliable and rugged and I will strongly recommend, Very ergonomic...Like this BT Mouse...Works nicely via BT, ergonomic design made my wrist easy. Good optical precision too!"

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    Product Description

    Eliminate the most common computer mouse issue—the cord. With the Best Buy Essentials Bluetooth Optical 6-Button Mouse, you can navigate the web without the limitations of a cable. Compatible with both Windows and Mac computers, simply pair the mouse using wireless Bluetooth 5.1 connection. It has 6 buttons that grant you total control, including left, right, scroll, DPI adjustment, forward and back. An ambidextrous design allows you to use your left or right hand. Optical technology detects when the mouse moves to deliver an accurate 1600 DPI response. We also included two (2) AAA batteries, so you’re ready to go right out of the box. Let us improve your computer navigation by going wireless with this Best Buy-backed mouse.
    See all Wireless & Bluetooth Mice
    Top comment

    "Nice Mouse...This device is very reliable and rugged and I will strongly recommend, Very ergonomic...Like this BT Mouse...Works nicely via BT, ergonomic design made my wrist easy. Good optical precision too!"

    See all customer reviews

    Product Description

    Eliminate the most common computer mouse issue—the cord. With the Best Buy Essentials Bluetooth Optical 6-Button Mouse, you can navigate the web without the limitations of a cable. Compatible with both Windows and Mac computers, simply pair the mouse using wireless Bluetooth 5.1 connection. It has 6 buttons that grant you total control, including left, right, scroll, DPI adjustment, forward and back. An ambidextrous design allows you to use your left or right hand. Optical technology detects when the mouse moves to deliver an accurate 1600 DPI response. We also included two (2) AAA batteries, so you’re ready to go right out of the box. Let us improve your computer navigation by going wireless with this Best Buy-backed mouse.
    See all Wireless & Bluetooth Mice
    Your price for this item is $16.99
    See all Wireless & Bluetooth Mice
  9. SteelSeries - Rival 3 Lightweight Wired Optical Gaming Mouse with Brilliant Prism RGB Lighting - Wired - Black - Front_Zoom
    Top comment

    "Mouse...The mouse is easy to and very ergonomic on my hand. The noise was easy to connect to the laptop....Great mouse...Easy installation, accurate and ergonomic instrument"

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    Product Description

    Stay in total control while playing with this SteelSeries Rival 3 mouse. The high-grade polymer construction offers reliable durability for seamless everyday use, and the ergonomic design adds comfort during extended periods of gaming. This SteelSeries Rival 3 mouse has a Brilliant Prism system with customizable lighting effects for syncing with your computer to deliver stunning light shows, and the mechanical switches ensure accuracy whether on the battlefield or race track.
    See all Gaming Mice
    Top comment

    "Mouse...The mouse is easy to and very ergonomic on my hand. The noise was easy to connect to the laptop....Great mouse...Easy installation, accurate and ergonomic instrument"

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    Product Description

    Stay in total control while playing with this SteelSeries Rival 3 mouse. The high-grade polymer construction offers reliable durability for seamless everyday use, and the ergonomic design adds comfort during extended periods of gaming. This SteelSeries Rival 3 mouse has a Brilliant Prism system with customizable lighting effects for syncing with your computer to deliver stunning light shows, and the mechanical switches ensure accuracy whether on the battlefield or race track.
    See all Gaming Mice
    Your price for this item is $23.99
    Save $6
    The comparable value price is $29.99
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  10. Logitech - MX Master 3S for Mac Bluetooth Laser Mouse with Ultrafast Scrolling - Wireless - Space Gray - Front_Zoom
    Top comment

    "More Ergonomic than Magic Mouse!...Perfect ergonomic mouse for mac that supports all the macos gestures...Goat mouse. Goat customization. Goat ergonomics. Goat"

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    Product Description

    Introducing Logitech MX Master 3S for Mac – an iconic mouse remastered for Mac. Now with Quiet Clicks and 8K DPI any-surface tracking for more feel and performance in your Mac computer set-up. Get creative with a complimentary 1-month Creative Cloud subscription with your purchase of MX Master 3S for Mac, and create, make, and do like never before.
    See all Wireless & Bluetooth Mice
    Top comment

    "More Ergonomic than Magic Mouse!...Perfect ergonomic mouse for mac that supports all the macos gestures...Goat mouse. Goat customization. Goat ergonomics. Goat"

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    Product Description

    Introducing Logitech MX Master 3S for Mac – an iconic mouse remastered for Mac. Now with Quiet Clicks and 8K DPI any-surface tracking for more feel and performance in your Mac computer set-up. Get creative with a complimentary 1-month Creative Cloud subscription with your purchase of MX Master 3S for Mac, and create, make, and do like never before.
    See all Wireless & Bluetooth Mice
    Your price for this item is $119.99
    See all Wireless & Bluetooth Mice
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