A:Answer Any motherboard will work with this, or any other AiO cooler. Some mid to high end motherboards might have a header labeled as dedicated for AiO’s, but any fan header will work just fine, other than the cpu fan header obviously. What you should take into consideration is what case you’re using, as some might not have enough room, either due to not having space for the radiator or blocking off access to the other parts of the motherboard. Most brand name cases will have a recommended size for radiators in their specs.
